Searchable abstracts of presentations at key conferences in endocrinology

ea0067o56 | Oral Presentations | EYES2019

Effects of novel antidiabetic agents on the arterial wall elastic properties as a marker of vascular function in patients with type 2 diabetes mellitus

Stampouloglou Panagiota , Siasos Gerasimos , Bletsa Evanthia , Batzias Konstantinos , Paschou Stavroula A , Antonopoulos Alexis , Tsigkou Vasiliki , Oikonomou Evangelos , Gouliopoulos Nikolaos , Thanopoulou Anastasia , Noutsou Marina , Vryonidou Andromahi , Tentolouris Nikolaos , Tousoulis Dimitris

Background: Arterial stiffness is a well-established surrogate marker of vascular properties and arterial dysfunction in patients with type 2 diabetes mellitus (DM2). We aimed to investigate whether optimization of DM2 therapy with, additional to metformin, novel antiglycemic agents may improve arterial wall properties and achieve better glycemic control.Methods: We enrolled 99 consecutive patients (male gender=63.3%) receiving metformin for DM2 who did ...

ea0063p602 | Diabetes, Obesity and Metabolism 2 | ECE2019

Platelet reactivity in patients with type 2 diabetes mellitus after treatment intensification with DPP-4i, SGLT-2i and GLP-1RA

Siasos Gerasimos , Paschou Stavroula A , Stampouloglou Panagiota K , Bletsa Evanthia , Batzias Konstantinos , Tsigkou Vasiliki , Antonopoulos Alexis , Oikonomou Evangelos , Gouliopoulos Nikolaos , Thanopoulou Anastasia , Noutsou Marina , Vryonidou Andromachi , Tentolouris Nikolaos , Tousoulis Dimitrios

Introduction: Patients with type 2 diabetes mellitus (T2DM) exert a higher risk for thrombotic events. Platelet reactivity may be used to assess prothrombotic state in such patients. The aim of this study was to investigate whether the administration of novel antidiabetic agents could influence the platelet reactivity in T2DM patients.Patients and methods: We enrolled 99 consecutive patients (males=63.3%), 64.92±8.3 years old, receiving metformin fo...